diff --git a/requirements_dev.txt b/requirements_dev.txt
index 1abcf36..18183e4 100644
--- a/requirements_dev.txt
+++ b/requirements_dev.txt
@@ -13,7 +13,7 @@ click==7.0
 pytest==5.0.0
 pytest-runner==5.1
 pytest-cov==2.7.1
-numpy==1.16.4
+numpy==1.22.0
 pandas==0.24.2
 requests==2.22.0
 aiohttp==3.5.4
diff --git a/setup.py b/setup.py
index 1c2fb3e..06bb16e 100644
--- a/setup.py
+++ b/setup.py
@@ -9,7 +9,7 @@
 with open('HISTORY.rst') as history_file:
     history = history_file.read()
 
-requirements = ["Click==7.0", "requests==2.22.0", "numpy==1.16.4",
+requirements = ["Click==7.0", "requests==2.22.0", "numpy==1.22.0",
                 "pandas==0.24.2", "aiohttp==3.5.4", "aiofiles==0.4.0",
                 "vcfpy2==0.1.2", "scikit-allel==1.2.1"]