diff --git a/packages/react-core/src/components/Dropdown/Dropdown.tsx b/packages/react-core/src/components/Dropdown/Dropdown.tsx
index 00c13f9782a..c556937a095 100644
--- a/packages/react-core/src/components/Dropdown/Dropdown.tsx
+++ b/packages/react-core/src/components/Dropdown/Dropdown.tsx
@@ -2,7 +2,7 @@ import React from 'react';
 import { css } from '@patternfly/react-styles';
 import { Menu, MenuContent, MenuProps } from '../Menu';
 import { Popper } from '../../helpers/Popper/Popper';
-import { useOUIAProps, OUIAProps } from '../../helpers';
+import { useOUIAProps, OUIAProps, onToggleArrowKeydownDefault } from '../../helpers';
 
 export interface DropdownPopperProps {
   /** Vertical direction of the popper. If enableFlip is set to true, this will set the initial direction before the popper flips. */
@@ -51,6 +51,8 @@ export interface DropdownProps extends MenuProps, OUIAProps {
   onOpenChange?: (isOpen: boolean) => void;
   /** Keys that trigger onOpenChange, defaults to tab and escape. It is highly recommended to include Escape in the array, while Tab may be omitted if the menu contains non-menu items that are focusable. */
   onOpenChangeKeys?: string[];
+  /** Callback to override the toggle keydown behavior. By default, when the toggle has focus and the menu is open, pressing the up/down arrow keys will focus a valid non-disabled menu item - the first item for the down arrow key and last item for the up arrow key. */
+  onToggleKeydown?: (event: KeyboardEvent) => void;
   /** Indicates if the menu should be without the outer box-shadow. */
   isPlain?: boolean;
   /** Indicates if the menu should be scrollable. */
@@ -85,6 +87,7 @@ const DropdownBase: React.FunctionComponent<DropdownProps> = ({
   toggle,
   shouldFocusToggleOnSelect = false,
   onOpenChange,
+  onToggleKeydown,
   isPlain,
   isScrollable,
   innerRef,
@@ -139,6 +142,14 @@ const DropdownBase: React.FunctionComponent<DropdownProps> = ({
           toggleRef.current?.focus();
         }
       }
+
+      if (toggleRef.current?.contains(event.target as Node)) {
+        if (onToggleKeydown) {
+          onToggleKeydown(event);
+        } else if (isOpen) {
+          onToggleArrowKeydownDefault(event, menuRef);
+        }
+      }
     };
 
     const handleClick = (event: MouseEvent) => {
@@ -163,6 +174,7 @@ const DropdownBase: React.FunctionComponent<DropdownProps> = ({
     toggleRef,
     onOpenChange,
     onOpenChangeKeys,
+    onToggleKeydown,
     shouldPreventScrollOnItemFocus,
     shouldFocusFirstItemOnOpen,
     focusTimeoutDelay
diff --git a/packages/react-core/src/components/Menu/MenuContainer.tsx b/packages/react-core/src/components/Menu/MenuContainer.tsx
index c1b96273b90..888e7c7dbe4 100644
--- a/packages/react-core/src/components/Menu/MenuContainer.tsx
+++ b/packages/react-core/src/components/Menu/MenuContainer.tsx
@@ -1,5 +1,5 @@
 import React from 'react';
-import { Popper } from '../../helpers/Popper/Popper';
+import { onToggleArrowKeydownDefault, Popper } from '../../helpers';
 
 export interface MenuPopperProps {
   /** Vertical direction of the popper. If enableFlip is set to true, this will set the initial direction before the popper flips. */
@@ -17,6 +17,7 @@ export interface MenuPopperProps {
   /** Flag to prevent the popper from overflowing its container and becoming partially obscured. */
   preventOverflow?: boolean;
 }
+
 export interface MenuContainerProps {
   /** Menu to be rendered */
   menu: React.ReactElement<any, string | React.JSXElementConstructor<any>>;
@@ -33,6 +34,8 @@ export interface MenuContainerProps {
   onOpenChange?: (isOpen: boolean) => void;
   /** Keys that trigger onOpenChange, defaults to tab and escape. It is highly recommended to include Escape in the array, while Tab may be omitted if the menu contains non-menu items that are focusable. */
   onOpenChangeKeys?: string[];
+  /** Callback to override the toggle keydown behavior. By default, when the toggle has focus and the menu is open, pressing the up/down arrow keys will focus a valid non-disabled menu item - the first item for the down arrow key and last item for the up arrow key. */
+  onToggleKeydown?: (event: KeyboardEvent) => void;
   /** z-index of the dropdown menu */
   zIndex?: number;
   /** Additional properties to pass to the Popper */
@@ -55,10 +58,11 @@ export const MenuContainer: React.FunctionComponent<MenuContainerProps> = ({
   toggle,
   toggleRef,
   onOpenChange,
+  onToggleKeydown,
   zIndex = 9999,
   popperProps,
   onOpenChangeKeys = ['Escape', 'Tab'],
-  shouldFocusFirstItemOnOpen = true,
+  shouldFocusFirstItemOnOpen = false,
   shouldPreventScrollOnItemFocus = true,
   focusTimeoutDelay = 0
 }: MenuContainerProps) => {
@@ -90,6 +94,14 @@ export const MenuContainer: React.FunctionComponent<MenuContainerProps> = ({
           toggleRef.current?.focus();
         }
       }
+
+      if (toggleRef.current?.contains(event.target as Node)) {
+        if (onToggleKeydown) {
+          onToggleKeydown(event);
+        } else if (isOpen) {
+          onToggleArrowKeydownDefault(event, menuRef);
+        }
+      }
     };
 
     const handleClick = (event: MouseEvent) => {
@@ -108,7 +120,16 @@ export const MenuContainer: React.FunctionComponent<MenuContainerProps> = ({
       window.removeEventListener('keydown', handleMenuKeys);
       window.removeEventListener('click', handleClick);
     };
-  }, [focusTimeoutDelay, isOpen, menuRef, onOpenChange, onOpenChangeKeys, shouldPreventScrollOnItemFocus, toggleRef]);
+  }, [
+    focusTimeoutDelay,
+    isOpen,
+    menuRef,
+    onOpenChange,
+    onOpenChangeKeys,
+    onToggleKeydown,
+    shouldPreventScrollOnItemFocus,
+    toggleRef
+  ]);
 
   return (
     <Popper
diff --git a/packages/react-core/src/components/Select/Select.tsx b/packages/react-core/src/components/Select/Select.tsx
index ace74b9eeb1..604881bf862 100644
--- a/packages/react-core/src/components/Select/Select.tsx
+++ b/packages/react-core/src/components/Select/Select.tsx
@@ -2,7 +2,7 @@ import React from 'react';
 import { css } from '@patternfly/react-styles';
 import { Menu, MenuContent, MenuProps } from '../Menu';
 import { Popper } from '../../helpers/Popper/Popper';
-import { getOUIAProps, OUIAProps, getDefaultOUIAId } from '../../helpers';
+import { getOUIAProps, OUIAProps, getDefaultOUIAId, onToggleArrowKeydownDefault } from '../../helpers';
 
 export interface SelectPopperProps {
   /** Vertical direction of the popper. If enableFlip is set to true, this will set the initial direction before the popper flips. */
@@ -62,6 +62,10 @@ export interface SelectProps extends MenuProps, OUIAProps {
   onOpenChange?: (isOpen: boolean) => void;
   /** Keys that trigger onOpenChange, defaults to tab and escape. It is highly recommended to include Escape in the array, while Tab may be omitted if the menu contains non-menu items that are focusable. */
   onOpenChangeKeys?: string[];
+  /** Callback to override the toggle keydown behavior. By default, when the toggle has focus and the menu is open, pressing the up/down arrow keys will focus a valid non-disabled menu item - the first item for the down arrow key and last item for the up arrow key. */
+  onToggleKeydown?: (event: KeyboardEvent) => void;
+  /** Select variant. For typeahead variant focus won't shift to menu items when pressing up/down arrows. */
+  variant?: 'default' | 'typeahead';
   /** Indicates if the select should be without the outer box-shadow */
   isPlain?: boolean;
   /** @hide Forwarded ref */
@@ -95,6 +99,8 @@ const SelectBase: React.FunctionComponent<SelectProps & OUIAProps> = ({
   shouldFocusFirstItemOnOpen = false,
   onOpenChange,
   onOpenChangeKeys = ['Escape', 'Tab'],
+  onToggleKeydown,
+  variant,
   isPlain,
   innerRef,
   zIndex = 9999,
@@ -144,6 +150,14 @@ const SelectBase: React.FunctionComponent<SelectProps & OUIAProps> = ({
           toggleRef.current?.focus();
         }
       }
+
+      if (toggleRef.current?.contains(event.target as Node)) {
+        if (onToggleKeydown) {
+          onToggleKeydown(event);
+        } else if (isOpen && variant !== 'typeahead') {
+          onToggleArrowKeydownDefault(event, menuRef);
+        }
+      }
     };
 
     const handleClick = (event: MouseEvent) => {
@@ -168,6 +182,7 @@ const SelectBase: React.FunctionComponent<SelectProps & OUIAProps> = ({
     toggleRef,
     onOpenChange,
     onOpenChangeKeys,
+    onToggleKeydown,
     shouldPreventScrollOnItemFocus,
     shouldFocusFirstItemOnOpen,
     focusTimeoutDelay
diff --git a/packages/react-core/src/components/Select/examples/SelectMultiTypeahead.tsx b/packages/react-core/src/components/Select/examples/SelectMultiTypeahead.tsx
index 41707fd1136..e4a1538a0ca 100644
--- a/packages/react-core/src/components/Select/examples/SelectMultiTypeahead.tsx
+++ b/packages/react-core/src/components/Select/examples/SelectMultiTypeahead.tsx
@@ -247,7 +247,7 @@ export const SelectMultiTypeahead: React.FunctionComponent = () => {
         !isOpen && closeMenu();
       }}
       toggle={toggle}
-      shouldFocusFirstItemOnOpen={false}
+      variant="typeahead"
     >
       <SelectList isAriaMultiselectable id="select-multi-typeahead-listbox">
         {selectOptions.map((option, index) => (
diff --git a/packages/react-core/src/components/Select/examples/SelectMultiTypeaheadCheckbox.tsx b/packages/react-core/src/components/Select/examples/SelectMultiTypeaheadCheckbox.tsx
index 030b62cc93b..2b46979959f 100644
--- a/packages/react-core/src/components/Select/examples/SelectMultiTypeaheadCheckbox.tsx
+++ b/packages/react-core/src/components/Select/examples/SelectMultiTypeaheadCheckbox.tsx
@@ -241,7 +241,7 @@ export const SelectMultiTypeaheadCheckbox: React.FunctionComponent = () => {
         !isOpen && closeMenu();
       }}
       toggle={toggle}
-      shouldFocusFirstItemOnOpen={false}
+      variant="typeahead"
     >
       <SelectList isAriaMultiselectable id="select-multi-typeahead-checkbox-listbox">
         {selectOptions.map((option, index) => (
diff --git a/packages/react-core/src/components/Select/examples/SelectMultiTypeaheadCreatable.tsx b/packages/react-core/src/components/Select/examples/SelectMultiTypeaheadCreatable.tsx
index e43c1afe1dd..256a7ee7afb 100644
--- a/packages/react-core/src/components/Select/examples/SelectMultiTypeaheadCreatable.tsx
+++ b/packages/react-core/src/components/Select/examples/SelectMultiTypeaheadCreatable.tsx
@@ -260,7 +260,7 @@ export const SelectMultiTypeaheadCreatable: React.FunctionComponent = () => {
         !isOpen && closeMenu();
       }}
       toggle={toggle}
-      shouldFocusFirstItemOnOpen={false}
+      variant="typeahead"
     >
       <SelectList isAriaMultiselectable id="select-multi-create-typeahead-listbox">
         {selectOptions.map((option, index) => (
diff --git a/packages/react-core/src/components/Select/examples/SelectTypeahead.tsx b/packages/react-core/src/components/Select/examples/SelectTypeahead.tsx
index 12ca075992d..e682de837fa 100644
--- a/packages/react-core/src/components/Select/examples/SelectTypeahead.tsx
+++ b/packages/react-core/src/components/Select/examples/SelectTypeahead.tsx
@@ -244,7 +244,7 @@ export const SelectTypeahead: React.FunctionComponent = () => {
         !isOpen && closeMenu();
       }}
       toggle={toggle}
-      shouldFocusFirstItemOnOpen={false}
+      variant="typeahead"
     >
       <SelectList id="select-typeahead-listbox">
         {selectOptions.map((option, index) => (
diff --git a/packages/react-core/src/components/Select/examples/SelectTypeaheadCreatable.tsx b/packages/react-core/src/components/Select/examples/SelectTypeaheadCreatable.tsx
index fda4f11bdfd..bd6cf9a3f8b 100644
--- a/packages/react-core/src/components/Select/examples/SelectTypeaheadCreatable.tsx
+++ b/packages/react-core/src/components/Select/examples/SelectTypeaheadCreatable.tsx
@@ -251,7 +251,7 @@ export const SelectTypeaheadCreatable: React.FunctionComponent = () => {
         !isOpen && closeMenu();
       }}
       toggle={toggle}
-      shouldFocusFirstItemOnOpen={false}
+      variant="typeahead"
     >
       <SelectList id="select-create-typeahead-listbox">
         {selectOptions.map((option, index) => (
diff --git a/packages/react-core/src/helpers/KeyboardHandler.tsx b/packages/react-core/src/helpers/KeyboardHandler.tsx
index afdaf7b5fb0..716e0703098 100644
--- a/packages/react-core/src/helpers/KeyboardHandler.tsx
+++ b/packages/react-core/src/helpers/KeyboardHandler.tsx
@@ -176,6 +176,33 @@ export const setTabIndex = (options: HTMLElement[]) => {
   }
 };
 
+/**
+ * This function is used in Dropdown, Select and MenuContainer as a default toggle keydown behavior. When the toggle has focus and the menu is open, pressing the up/down arrow keys will focus a valid non-disabled menu item - the first item for the down arrow key and last item for the up arrow key.
+ *
+ * @param event Event triggered by the keyboard
+ * @param menuRef Menu reference
+ */
+export const onToggleArrowKeydownDefault = (event: KeyboardEvent, menuRef: React.RefObject<HTMLDivElement>) => {
+  if (event.key !== 'ArrowDown' && event.key !== 'ArrowUp') {
+    return;
+  }
+
+  event.preventDefault();
+
+  const listItems = Array.from(menuRef.current?.querySelectorAll('li'));
+  const focusableElements = listItems
+    .map((li) => li.querySelector('button:not(:disabled),input:not(:disabled),a:not([aria-disabled="true"])'))
+    .filter((el) => el !== null);
+
+  let focusableElement: Element;
+  if (event.key === 'ArrowDown') {
+    focusableElement = focusableElements[0];
+  } else {
+    focusableElement = focusableElements[focusableElements.length - 1];
+  }
+  focusableElement && (focusableElement as HTMLElement).focus();
+};
+
 class KeyboardHandler extends React.Component<KeyboardHandlerProps> {
   static displayName = 'KeyboardHandler';
   static defaultProps: KeyboardHandlerProps = {
diff --git a/packages/react-templates/src/components/Select/MultiTypeaheadSelect.tsx b/packages/react-templates/src/components/Select/MultiTypeaheadSelect.tsx
index 5beb2b9d7b5..552b4594d51 100644
--- a/packages/react-templates/src/components/Select/MultiTypeaheadSelect.tsx
+++ b/packages/react-templates/src/components/Select/MultiTypeaheadSelect.tsx
@@ -320,7 +320,7 @@ export const MultiTypeaheadSelectBase: React.FunctionComponent<MultiTypeaheadSel
         !isOpen && closeMenu();
       }}
       toggle={toggle}
-      shouldFocusFirstItemOnOpen={false}
+      variant="typeahead"
       ref={innerRef}
       {...props}
     >
diff --git a/packages/react-templates/src/components/Select/TypeaheadSelect.tsx b/packages/react-templates/src/components/Select/TypeaheadSelect.tsx
index b674a227d5d..b0e14b5282b 100644
--- a/packages/react-templates/src/components/Select/TypeaheadSelect.tsx
+++ b/packages/react-templates/src/components/Select/TypeaheadSelect.tsx
@@ -361,7 +361,7 @@ export const TypeaheadSelectBase: React.FunctionComponent<TypeaheadSelectProps>
         !isOpen && closeMenu();
       }}
       toggle={toggle}
-      shouldFocusFirstItemOnOpen={false}
+      variant="typeahead"
       ref={innerRef}
       {...props}
     >