diff --git a/python/ql/lib/semmle/python/Exprs.qll b/python/ql/lib/semmle/python/Exprs.qll
index 47e31bb07cdd..accc370481aa 100644
--- a/python/ql/lib/semmle/python/Exprs.qll
+++ b/python/ql/lib/semmle/python/Exprs.qll
@@ -746,6 +746,24 @@ class Guard extends Guard_ {
   override Expr getASubExpression() { result = this.getTest() }
 }
 
+/** An annotation, such as the `int` part of `x: int` */
+class Annotation extends Expr {
+  Annotation() {
+    this = any(AnnAssign a).getAnnotation()
+    or
+    exists(Arguments args |
+      this in [
+          args.getAnAnnotation(),
+          args.getAKwAnnotation(),
+          args.getKwargannotation(),
+          args.getVarargannotation()
+        ]
+    )
+    or
+    this = any(FunctionExpr f).getReturns()
+  }
+}
+
 /* Expression Contexts */
 /** A context in which an expression used */
 class ExprContext extends ExprContext_ { }
diff --git a/python/ql/src/Variables/UnusedModuleVariable.ql b/python/ql/src/Variables/UnusedModuleVariable.ql
index 869c31cb4fa1..c9009d9bf369 100644
--- a/python/ql/src/Variables/UnusedModuleVariable.ql
+++ b/python/ql/src/Variables/UnusedModuleVariable.ql
@@ -34,6 +34,14 @@ predicate complex_all(Module m) {
   )
 }
 
+predicate used_in_forward_declaration(Name used, Module mod) {
+  exists(StringLiteral s, Annotation annotation |
+    s.getS() = used.getId() and
+    s.getEnclosingModule() = mod and
+    annotation.getASubExpression*() = s
+  )
+}
+
 predicate unused_global(Name unused, GlobalVariable v) {
   not exists(ImportingStmt is | is.contains(unused)) and
   forex(DefinitionNode defn | defn.getNode() = unused |
@@ -55,7 +63,8 @@ predicate unused_global(Name unused, GlobalVariable v) {
     unused.defines(v) and
     not name_acceptable_for_unused_variable(v) and
     not complex_all(unused.getEnclosingModule())
-  )
+  ) and
+  not used_in_forward_declaration(unused, unused.getEnclosingModule())
 }
 
 from Name unused, GlobalVariable v
diff --git a/python/ql/src/change-notes/2025-03-04-fix-forward-annotation-fp-in-unused-global-var-query.md b/python/ql/src/change-notes/2025-03-04-fix-forward-annotation-fp-in-unused-global-var-query.md
new file mode 100644
index 000000000000..78142ea3fc68
--- /dev/null
+++ b/python/ql/src/change-notes/2025-03-04-fix-forward-annotation-fp-in-unused-global-var-query.md
@@ -0,0 +1,5 @@
+---
+category: fix
+---
+
+- The `py/unused-global-variable` now no longer flags variables that are only used in forward references (e.g. the `Foo` in `def bar(x: "Foo"): ...`).
diff --git a/python/ql/test/query-tests/Variables/unused/variables_test.py b/python/ql/test/query-tests/Variables/unused/variables_test.py
index ff8ac50a541c..611b9fbd6b2a 100644
--- a/python/ql/test/query-tests/Variables/unused/variables_test.py
+++ b/python/ql/test/query-tests/Variables/unused/variables_test.py
@@ -137,3 +137,21 @@ def test_dict_unpacking(queryset, field_name, value):
     for tag in value.split(','):
         queryset = queryset.filter(**{field_name + '__name': tag})
     return queryset
+
+from typing import TYPE_CHECKING
+
+if TYPE_CHECKING:
+    ParamAnnotation = int
+    ReturnAnnotation = int
+    AssignmentAnnotation = int
+    ForwardParamAnnotation = int
+    ForwardReturnAnnotation = int
+    ForwardAssignmentAnnotation = int
+
+def test_direct_annotation(x: ParamAnnotation) -> ReturnAnnotation:
+    if x:
+        y : AssignmentAnnotation = 1
+
+def test_forward_annotation(x: "ForwardParamAnnotation") -> "ForwardReturnAnnotation":
+    if x:
+        y : "ForwardAssignmentAnnotation" = 1