diff --git a/packages/target-ethers-v5/src/codegen/index.ts b/packages/target-ethers-v5/src/codegen/index.ts
index 239e1a488..6f1a98007 100644
--- a/packages/target-ethers-v5/src/codegen/index.ts
+++ b/packages/target-ethers-v5/src/codegen/index.ts
@@ -240,6 +240,23 @@ export function codegenAbstractContractFactory(contract: Contract, abi: any): st
   `
 }
 
+// Earlier versions of the vyper compiler included the 'gas' estimates as a member
+// in the vyper-generated abi object.
+// This breaks the typechain auto-generation code, since gas is a number and not stringified.
+// Further, even if it were stringified, the gas estimates are generally incorrect.
+// So the 'gas' member is manually removed from the abi in the generated typechain.
+function stringifyAbi(abi: any): string {
+  if (typeof abi === 'object') {
+    const abiNoGas = abi.map((element: any) => {
+      const { gas: _, ...withoutGas } = element
+      return withoutGas
+    })
+    return JSON.stringify(abiNoGas, null, 2)
+  }
+
+  return JSON.stringify(abi, null, 2)
+}
+
 function codegenCommonContractFactory(contract: Contract, abi: any): { header: string; body: string } {
   const imports: Set<string> = new Set([contract.name, contract.name + 'Interface'])
 
@@ -257,7 +274,7 @@ function codegenCommonContractFactory(contract: Contract, abi: any): { header: s
   const header = `
   import type { ${[...imports.values()].join(', ')} } from "${contractTypesImportPath}";
 
-  const _abi = ${JSON.stringify(abi, null, 2)};
+  const _abi = ${stringifyAbi(abi)};
   `.trim()
 
   const body = `
diff --git a/packages/target-ethers-v5/test/generation.test.ts b/packages/target-ethers-v5/test/generation.test.ts
index ad1467674..8c94f1ab4 100644
--- a/packages/target-ethers-v5/test/generation.test.ts
+++ b/packages/target-ethers-v5/test/generation.test.ts
@@ -37,6 +37,35 @@ describe('Ethers generation edge cases', () => {
     expect(source).toEqual(expect.stringMatching(/export class TestContract__factory extends ContractFactory \{/))
     expect(source).toEqual(expect.stringMatching(/static linkBytecode\(/))
   })
+
+  it('should exclude gas field from ABI', () => {
+    const abi = [
+      {
+        stateMutability: 'view',
+        type: 'function',
+        name: 'foo',
+        inputs: [
+          {
+            name: 'bar',
+            type: 'address',
+          },
+        ],
+        outputs: [
+          {
+            name: '',
+            type: 'uint256',
+          },
+        ],
+        gas: 3135,
+      },
+    ]
+
+    const source = codegenContractFactory(DEFAULT_FLAGS, emptyContract, abi, {
+      bytecode: '{{BYTECODE}}',
+    })
+
+    expect(source).not.toEqual(expect.stringMatching(/"gas":/))
+  })
 })
 
 describe(generateEventFilters.name, () => {