diff --git a/packages/react-devtools-shared/src/__tests__/utils-test.js b/packages/react-devtools-shared/src/__tests__/utils-test.js
index 9b9e82102cc..aedc8d2b1be 100644
--- a/packages/react-devtools-shared/src/__tests__/utils-test.js
+++ b/packages/react-devtools-shared/src/__tests__/utils-test.js
@@ -393,6 +393,24 @@ describe('utils', () => {
         165558,
       ]);
     });
+
+    it('should handle malicious input without ReDoS vulnerability', () => {
+      // This test ensures the Firefox stack regex doesn't exhibit catastrophic
+      // backtracking (ReDoS) when processing malicious input patterns.
+      // See: https://github.com/facebook/react/issues/35490
+      const nullChar = String.fromCharCode(0);
+      const maliciousInput =
+        ' ' + ('"' + nullChar).repeat(2000) + '\r!\r!' + '\n';
+
+      const startTime = Date.now();
+      // This should complete quickly (< 100ms) instead of hanging for seconds
+      const result = extractLocationFromComponentStack(maliciousInput);
+      const elapsedTime = Date.now() - startTime;
+
+      // The result should be null (no valid stack frame) and complete quickly
+      expect(result).toEqual(null);
+      expect(elapsedTime).toBeLessThan(100);
+    });
   });
 
   describe('symbolicateSource', () => {
diff --git a/packages/react-devtools-shared/src/backend/utils/parseStackTrace.js b/packages/react-devtools-shared/src/backend/utils/parseStackTrace.js
index e18c2d7baa1..35ed53631e8 100644
--- a/packages/react-devtools-shared/src/backend/utils/parseStackTrace.js
+++ b/packages/react-devtools-shared/src/backend/utils/parseStackTrace.js
@@ -59,7 +59,11 @@ function parseStackTraceFromChromeStack(
   return parsedFrames;
 }
 
-const firefoxFrameRegExp = /^((?:.*".+")?[^@]*)@(.+):(\d+):(\d+)$/;
+// Fix ReDoS vulnerability: Changed `.*".+"` to `"[^"]+"` to prevent catastrophic backtracking.
+// The original pattern `(?:.*".+")?` with nested quantifiers could cause exponential time
+// complexity on malicious inputs. Using `"[^"]+"` (negated character class) is O(n) and
+// maintains the same matching behavior for valid Firefox stack frames.
+const firefoxFrameRegExp = /^((?:"[^"]+")?[^@]*)@(.+):(\d+):(\d+)$/;
 function parseStackTraceFromFirefoxStack(
   stack: string,
   skipFrames: number,