diff --git a/cmake/Modules/Platform/Emscripten.cmake b/cmake/Modules/Platform/Emscripten.cmake
index 90e58037750be..293aad9f76358 100644
--- a/cmake/Modules/Platform/Emscripten.cmake
+++ b/cmake/Modules/Platform/Emscripten.cmake
@@ -268,12 +268,15 @@ endif()
 
 set(CMAKE_EXECUTABLE_SUFFIX ".js")
 
-set(CMAKE_C_USE_RESPONSE_FILE_FOR_LIBRARIES 1)
-set(CMAKE_CXX_USE_RESPONSE_FILE_FOR_LIBRARIES 1)
-set(CMAKE_C_USE_RESPONSE_FILE_FOR_OBJECTS 1)
-set(CMAKE_CXX_USE_RESPONSE_FILE_FOR_OBJECTS 1)
-set(CMAKE_C_USE_RESPONSE_FILE_FOR_INCLUDES 1)
-set(CMAKE_CXX_USE_RESPONSE_FILE_FOR_INCLUDES 1)
+if (CMAKE_HOST_WIN32)
+  # See https://github.com/emscripten-core/emscripten/issues/2386
+  set(CMAKE_C_USE_RESPONSE_FILE_FOR_LIBRARIES 1)
+  set(CMAKE_CXX_USE_RESPONSE_FILE_FOR_LIBRARIES 1)
+  set(CMAKE_C_USE_RESPONSE_FILE_FOR_OBJECTS 1)
+  set(CMAKE_CXX_USE_RESPONSE_FILE_FOR_OBJECTS 1)
+  set(CMAKE_C_USE_RESPONSE_FILE_FOR_INCLUDES 1)
+  set(CMAKE_CXX_USE_RESPONSE_FILE_FOR_INCLUDES 1)
+endif()
 
 set(CMAKE_C_RESPONSE_FILE_LINK_FLAG "@")
 set(CMAKE_CXX_RESPONSE_FILE_LINK_FLAG "@")