diff --git a/helm_chart/HyperPodHelmChart/charts/gpu-operator/config/default-mig-config.yaml b/helm_chart/HyperPodHelmChart/charts/gpu-operator/config/default-mig-config.yaml
index 8f4943d7..f18523ed 100644
--- a/helm_chart/HyperPodHelmChart/charts/gpu-operator/config/default-mig-config.yaml
+++ b/helm_chart/HyperPodHelmChart/charts/gpu-operator/config/default-mig-config.yaml
@@ -341,12 +341,90 @@ mig-configs:
         "1g.24gb": 2
         "2g.48gb": 1
 
+  # P6-B300 (Blackwell Ultra, 288GB HBM3e, ~269GB usable) profiles
+  # Profiles: 1g.34gb (x7), 1g.67gb (x4), 2g.67gb (x3), 3g.135gb (x2), 4g.135gb (x1), 7g.269gb (x1)
+  # Upstream ref: NVIDIA GPU Operator v25.3.0, device-filter 0x318210DE
+
+  all-1g.34gb:
+    - devices: all
+      mig-enabled: true
+      mig-devices:
+        "1g.34gb": 7
+
   all-1g.67gb:
     - devices: all
       mig-enabled: true
       mig-devices:
         "1g.67gb": 4
 
+  all-2g.67gb:
+    - devices: all
+      mig-enabled: true
+      mig-devices:
+        "2g.67gb": 3
+
+  all-3g.135gb:
+    - devices: all
+      mig-enabled: true
+      mig-devices:
+        "3g.135gb": 2
+
+  all-4g.135gb:
+    - devices: all
+      mig-enabled: true
+      mig-devices:
+        "4g.135gb": 1
+
+  all-7g.269gb:
+    - devices: all
+      mig-enabled: true
+      mig-devices:
+        "7g.269gb": 1
+
+  mixed-1-3g.135gb-1-4g.135gb:
+    - devices: all
+      mig-enabled: true
+      mig-devices:
+        "3g.135gb": 1
+        "4g.135gb": 1
+
+  mixed-1-1g.34gb-1-2g.67gb-1-4g.135gb:
+    - devices: all
+      mig-enabled: true
+      mig-devices:
+        "1g.34gb": 1
+        "2g.67gb": 1
+        "4g.135gb": 1
+
+  mixed-3-1g.34gb-1-4g.135gb:
+    - devices: all
+      mig-enabled: true
+      mig-devices:
+        "1g.34gb": 3
+        "4g.135gb": 1
+
+  mixed-1-1g.34gb-1-2g.67gb-1-3g.135gb:
+    - devices: all
+      mig-enabled: true
+      mig-devices:
+        "1g.34gb": 1
+        "2g.67gb": 1
+        "3g.135gb": 1
+
+  mixed-3-1g.34gb-1-3g.135gb:
+    - devices: all
+      mig-enabled: true
+      mig-devices:
+        "1g.34gb": 3
+        "3g.135gb": 1
+
+  mixed-2-2g.67gb-1-3g.135gb:
+    - devices: all
+      mig-enabled: true
+      mig-devices:
+        "2g.67gb": 2
+        "3g.135gb": 1
+
   mixed-2-1g.34gb-1-2g.67gb-1-3g.135gb:
     - devices: all
       mig-enabled: true
@@ -354,3 +432,31 @@ mig-configs:
         "1g.34gb": 2
         "2g.67gb": 1
         "3g.135gb": 1
+
+  mixed-4-1g.34gb-1-3g.135gb:
+    - devices: all
+      mig-enabled: true
+      mig-devices:
+        "1g.34gb": 4
+        "3g.135gb": 1
+
+  mixed-1-1g.34gb-3-2g.67gb:
+    - devices: all
+      mig-enabled: true
+      mig-devices:
+        "1g.34gb": 1
+        "2g.67gb": 3
+
+  mixed-3-1g.34gb-2-2g.67gb:
+    - devices: all
+      mig-enabled: true
+      mig-devices:
+        "1g.34gb": 3
+        "2g.67gb": 2
+
+  mixed-5-1g.34gb-1-2g.67gb:
+    - devices: all
+      mig-enabled: true
+      mig-devices:
+        "1g.34gb": 5
+        "2g.67gb": 1
diff --git a/src/sagemaker/hyperpod/training/constants.py b/src/sagemaker/hyperpod/training/constants.py
index 29f58fa8..59230365 100644
--- a/src/sagemaker/hyperpod/training/constants.py
+++ b/src/sagemaker/hyperpod/training/constants.py
@@ -132,6 +132,7 @@
     'ml.p5e.48xlarge': ['mig-1g.18gb', 'mig-1g.35gb', 'mig-2g.35gb', 'mig-3g.71gb', 'mig-4g.71gb', 'mig-7g.141gb'],
     'ml.p5en.48xlarge': ['mig-1g.18gb', 'mig-1g.35gb', 'mig-2g.35gb', 'mig-3g.71gb', 'mig-4g.71gb', 'mig-7g.141gb'],
     'p6-b200.48xlarge': ['mig-1g.23gb', 'mig-1g.45gb', 'mig-2g.45gb', 'mig-3g.90gb', 'mig-4g.90gb', 'mig-7g.180gb'],
+    'ml.p6-b300.48xlarge': ['mig-1g.34gb', 'mig-1g.67gb', 'mig-2g.67gb', 'mig-3g.135gb', 'mig-4g.135gb', 'mig-7g.269gb'],
     'ml.p6e-gb200.36xlarge': ['mig-1g.23gb', 'mig-1g.47gb', 'mig-2g.47gb', 'mig-3g.93gb', 'mig-4g.93gb', 'mig-7g.186gb'],
     'ml.g7e.2xlarge': ['mig-1g.24gb', 'mig-2g.48gb', 'mig-4g.96gb'],
     'ml.g7e.4xlarge': ['mig-1g.24gb', 'mig-2g.48gb', 'mig-4g.96gb'],